BDBM515167 US11098058, Example 103::US11098058, Example 34

SMILES c1ccc(cc1)[C@@H]2C[C@@H](c3n2nc(n3)C(=O)C4CC4)F

InChI Key InChIKey=LMXPZWQVDDSYHH-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515167   

LigandChemical structure of BindingDB Monomer ID 515167BDBM515167(US11098058, Example 103 | US11098058, Example 34)
Affinity DataKi:  3.60nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 515167BDBM515167(US11098058, Example 103 | US11098058, Example 34)
Affinity DataKi:  7.90nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)