BDBM50668443 CHEMBL6191865

SMILES Cn1cc(-c2ccncc2)c2cc3ccncc3cc21

InChI Key InChIKey=YTSCYPFGCMNOFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50668443   

TargetSerine/threonine-protein kinase haspin(Human)
Universite Clermont Auvergne

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668443BDBM50668443(CHEMBL6191865)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human haspin kinase domain (470 to 798 residues) extracted from bacteria using histone H3 (1 to 21) peptide as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Universite Clermont Auvergne

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668443BDBM50668443(CHEMBL6191865)
Affinity DataIC50: 339nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain (1 to 499 residues) extracted from bacteria using KKISGRLSPIMTEQ as substrate incubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
Universite Clermont Auvergne

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668443BDBM50668443(CHEMBL6191865)
Affinity DataIC50: 546nMAssay Description:Inhibition of recombinant mouse CLK1 extracted from bacteria using GRSRSRSRSRSR as substrate incubated for 30 mins in presence of ATP by ADP-Glo kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Universite Clermont Auvergne

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668443BDBM50668443(CHEMBL6191865)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant human PIM-1 extracted from bacteria using histone H1 as substrate incubated for 30 mins in presence of ATP by ADP-Glo kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed