BDBM50667154 CHEMBL6174055

SMILES Cn1cnnc1[C@]1(c2cccc(N3Cc4c(Cl)cc(CNCC5CCC5)cc4C3=O)c2)C[C@@H](Cl)C1

InChI Key InChIKey=JPCMZAKLAQOVEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667154   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667154BDBM50667154(CHEMBL6174055)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of biotin-tagged Cbl-B (unknown origin) pre-incubated with compound for 60 min followed by Lck addition and measured after 90 mins in pres...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed