BDBM50664115 CHEMBL6134510

SMILES Cn1cc(-c2cc3ncccc3c(-c3ccc(N4CC5CC(C4)N5Cc4ccc(Cl)nc4)nc3)n2)cn1

InChI Key InChIKey=GKUJWLGWPRMIHR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50664115   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664115BDBM50664115(CHEMBL6134510)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664115BDBM50664115(CHEMBL6134510)
Affinity DataIC50: 5.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664115BDBM50664115(CHEMBL6134510)
Affinity DataIC50: 9.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664115BDBM50664115(CHEMBL6134510)
Affinity DataIC50: 361nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed