BDBM50664114 CHEMBL6143395

SMILES Cn1cc(-c2cc3ncccc3c(-c3ccc(N4CC5CC(C4)N5Cc4ccc(F)nc4)nc3)n2)cn1

InChI Key InChIKey=QWXUTYPPSZGJQW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50664114   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664114BDBM50664114(CHEMBL6143395)
Affinity DataIC50: 5.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664114BDBM50664114(CHEMBL6143395)
Affinity DataIC50: 9.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664114BDBM50664114(CHEMBL6143395)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Affiliated Hengyang Hospital of Hunan Normal University & Hengyang Central Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664114BDBM50664114(CHEMBL6143395)
Affinity DataIC50: 237nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed