BDBM50657987 CHEMBL6163911

SMILES CCc1c(N2CCN(C(=O)c3cncc4cc[nH]c34)CC2)c(=O)n2nc(C3=CCOCC3)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657987   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657987BDBM50657987(CHEMBL6163911)
Affinity DataIC50: 123nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657987BDBM50657987(CHEMBL6163911)
Affinity DataIC50: 157nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed