BDBM50657730 CHEMBL6144731

SMILES CN1CC(F)(F)CCN(C)[C@H]2CC[C@@H](C2)Nc2ncc(C(F)(F)F)c(n2)-c2c[nH]c3c(P(C)(C)=O)c(ccc23)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50657730   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataKd:  0.180nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-dependent kinase 18(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase D3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMitogen-activated protein kinase 15(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 7.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-Y(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase D1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMitogen-activated protein kinase 7(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-dependent kinase 2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase D2(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHomeodomain-interacting protein kinase 4(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-dependent kinase 12(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 62nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 146nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCyclin-dependent kinase 9(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 258nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 292nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase ULK1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 368nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase TAO1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657730BDBM50657730(CHEMBL6144731)
Affinity DataIC50: 546nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed