BDBM50657464 CHEMBL6152394

SMILES CCc1cc(C#N)cc(F)c1N(C)c1cc2c(ncn2C)c(NC(=O)[C@H]2C[C@H]2F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50657464   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657464BDBM50657464(CHEMBL6152394)
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK1(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657464BDBM50657464(CHEMBL6152394)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657464BDBM50657464(CHEMBL6152394)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK3(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657464BDBM50657464(CHEMBL6152394)
Affinity DataIC50: 348nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed