BDBM50657462 CHEMBL6102457

SMILES CCc1cc(C#N)cc(F)c1N(C)c1cc2c(ncn2C)c(NC(=O)C2CC2(F)F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50657462   

TargetTyrosine-protein kinase JAK1(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657462BDBM50657462(CHEMBL6102457)
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657462BDBM50657462(CHEMBL6102457)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657462BDBM50657462(CHEMBL6102457)
Affinity DataIC50: 137nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK3(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657462BDBM50657462(CHEMBL6102457)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed