BDBM50657456 CHEMBL6152057

SMILES CCc1cc(C#N)cc(F)c1N(C)c1cc2c(ncn2C)c(NC(=O)OC)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50657456   

TargetTyrosine-protein kinase JAK1(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657456BDBM50657456(CHEMBL6152057)
Affinity DataIC50: 7.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657456BDBM50657456(CHEMBL6152057)
Affinity DataIC50: 8.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657456BDBM50657456(CHEMBL6152057)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK3(Human)
Galapagos NV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657456BDBM50657456(CHEMBL6152057)
Affinity DataIC50: 458nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed