BDBM50657031 CHEMBL6145305

SMILES Cc1nn(-c2ccc(F)cc2)c(-n2ccnc2)c1C(=O)NCc1cccnc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50657031   

TargetAurora kinase A(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetAurora kinase B(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetAurora kinase C(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 132nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 141nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase ABL1(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 171nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetTyrosine-protein kinase JAK2(Human)
Children's Hospital Affiliated to Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657031BDBM50657031(CHEMBL6145305)
Affinity DataIC50: 254nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed