BDBM50656372 CHEMBL6134359

SMILES N#CCCc1cc2c(nc(-c3ccncn3)c3cc(CN4CCOCC4=O)n([C@H]4[C@H]5CN[C@@H]4C5)c32)c(F)c1-c1cccc2ccc(F)cc12

InChI Key InChIKey=NTJZENDZDQZYQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50656372   

TargetGTPase KRas(Human)
Incyte Corporation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656372BDBM50656372(CHEMBL6134359)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed