BDBM50655865 CHEMBL6120288

SMILES COc1cn([C@H](Cc2ccccc2)c2cn(-c3ccc(C(=O)O)cc3)nn2)c(=O)cc1-c1cc(Cl)ccc1-n1cc(Cl)nn1

InChI Key InChIKey=AIZUZOZYGWNPIO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50655865   

TargetCoagulation factor XI(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655865BDBM50655865(CHEMBL6120288)
Affinity DataIC50: 96nMAssay Description:Inhibition of human Factor XIa using Boc-Glu(OBzl)-Ala-Arg-AMC assessed as AMC release preincubated for 15 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655865BDBM50655865(CHEMBL6120288)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human PKa using H-Pro-Phe-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProthrombin(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655865BDBM50655865(CHEMBL6120288)
Affinity DataIC50: 4.69E+4nMAssay Description:Inhibition of human thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCoagulation factor X(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655865BDBM50655865(CHEMBL6120288)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Factor Xa using Boc-Ile-Glu-Gly-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTrypsin(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655865BDBM50655865(CHEMBL6120288)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human trypsin using Boc-Ile-Glu-Gly-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed