BDBM50655352 CHEMBL6102644

SMILES CCc1nc(C)c(-c2cc3c(=O)n(C)cc(-c4cc(C(C)(C)O)ccc4Oc4c(C)cc(F)cc4C)c3o2)[nH]1

InChI Key InChIKey=QYKGZNGGCIODBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50655352   

TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655352BDBM50655352(CHEMBL6102644)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655352BDBM50655352(CHEMBL6102644)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655352BDBM50655352(CHEMBL6102644)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of ASK1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed