BDBM50655076 CHEMBL6146800

SMILES O=C(O)[C@H](c1cc(F)ccc1[C@H]1CCOC1)N1CC[C@@H](OCCCCc2ccc3c(n2)NCCC3)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50655076   

TargetIntegrin alpha-V/beta-6(Human)
Morphic Therapeutic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655076BDBM50655076(CHEMBL6146800)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at full length human ERalpha receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetIntegrin alpha-V/beta-6(Human)
Morphic Therapeutic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655076BDBM50655076(CHEMBL6146800)
Affinity DataIC50: 90nMAssay Description:Inhibition of human sEH using epoxy flour 7 as substrate measured after 30 mins by cell-based fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetIntegrin alpha-V/beta-1(Human)
Morphic Therapeutic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655076BDBM50655076(CHEMBL6146800)
Affinity DataIC50: 110nMAssay Description:Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetIntegrin alpha-V/beta-8(Human)
Morphic Therapeutic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655076BDBM50655076(CHEMBL6146800)
Affinity DataIC50: 190nMAssay Description:Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Lucife...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed