BDBM50654791 CHEMBL6152632

SMILES CC(C)(C)OC(=O)Cn1cc(-c2ccc3c(c2)ncn3-c2ccc(CC(=O)Nc3cc(C(C)(C)C)no3)cc2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50654791   

TargetVascular endothelial growth factor receptor 3(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654791BDBM50654791(CHEMBL6152632)
Affinity DataIC50: 2.20nMAssay Description:Inhibition TRKA (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654791BDBM50654791(CHEMBL6152632)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as reduction in amyloidbeta 40 level after 24 hrs by cell-based sandwich ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654791BDBM50654791(CHEMBL6152632)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human Nav1.7 at -60 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed