BDBM50654785 CHEMBL6146585

SMILES CC(C)c1cc(NC(=O)Cc2ccc(-n3cnc4cc(-c5cnn(C)c5)ccc43)cc2)on1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50654785   

TargetVascular endothelial growth factor receptor 3(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654785BDBM50654785(CHEMBL6146585)
Affinity DataIC50: 0.560nMAssay Description:Agonist activity at FXR (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654785BDBM50654785(CHEMBL6146585)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as reduction in amyloidbeta 40 level after 24 hrs by cell-based sandwich ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654785BDBM50654785(CHEMBL6146585)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Nav1.5 at -50 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed