BDBM50654417 CHEMBL6102198

SMILES O=C(c1ccc(I)cc1)N1CCC(n2cncc2-c2ccc(OS(=O)(=O)c3cccc4cnccc34)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50654417   

TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654417BDBM50654417(CHEMBL6102198)
Affinity DataIC50: 0.25nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetP2X purinoceptor 7(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654417BDBM50654417(CHEMBL6102198)
Affinity DataIC50: 7.10nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed