BDBM50654200 Dersimelagon phosphoric acid::MT-7117 phosphate::Dersimelagon phosphate

SMILES COC[C@H]1CN(C(=O)[C@]2(F)CN(C3CCCC3)C[C@H]2c2ccc(OC)cc2)C[C@@H]1c1ccc(C(F)(F)F)cc1N1CCC(C(=O)O)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50654200   

TargetMelanocyte-stimulating hormone receptor(Human)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654200BDBM50654200(Dersimelagon phosphoric acid | MT-7117 phosphate |...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654200BDBM50654200(Dersimelagon phosphoric acid | MT-7117 phosphate |...)
Affinity DataEC50:  8.20nMAssay Description:Inhibition of Nav1.5 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMelanocortin receptor 4(Human)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654200BDBM50654200(Dersimelagon phosphoric acid | MT-7117 phosphate |...)
Affinity DataKi:  33nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMelanocortin receptor 5(Human)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654200BDBM50654200(Dersimelagon phosphoric acid | MT-7117 phosphate |...)
Affinity DataKi:  486nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMelanocortin receptor 3(Human)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654200BDBM50654200(Dersimelagon phosphoric acid | MT-7117 phosphate |...)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of Nav1.7 by cell based whole-cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed