BDBM50653859 CHEMBL6091929

SMILES Cc1cc(-c2ccc(NC(=O)Nc3ccc(C(C)(C)C)cc3)cc2)c2c(N)noc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50653859   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 1nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 55nMAssay Description:Inhibition of Akt1 by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 97nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 113nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMuscle, skeletal receptor tyrosine-protein kinase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653859BDBM50653859(CHEMBL6091929)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed