BDBM50653804 CHEMBL6145158

SMILES C=CC(=O)N1C[C@H](C)N(c2nc(=O)n3c4nc(c(F)cc24)-c2c(F)cc(F)cc2OCC(F)(F)CCc2ccnc(C(C)C)c2-3)C[C@H]1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50653804   

TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653804BDBM50653804(CHEMBL6145158)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Merck & Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653804BDBM50653804(CHEMBL6145158)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed