BDBM50653731 CHEMBL6133471

SMILES O=C(Nc1ccc(Oc2ccnc(NC(=O)N3CC(O)C3)c2)c(F)c1)c1cn(-c2cccnc2)nn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50653731   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653731BDBM50653731(CHEMBL6133471)
Affinity DataIC50: 69nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653731BDBM50653731(CHEMBL6133471)
Affinity DataIC50: 112nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653731BDBM50653731(CHEMBL6133471)
Affinity DataIC50: 131nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653731BDBM50653731(CHEMBL6133471)
Affinity DataIC50: 475nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653731BDBM50653731(CHEMBL6133471)
Affinity DataIC50: 588nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed