BDBM50653416 CHEMBL6103295

SMILES Cc1cccc(N2CCN(c3nnc4n3-c3ccc(Cl)cc3CC3(C4)OCCO3)CC2)c1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50653416   

TargetVasopressin V1a receptor(Mouse)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653416BDBM50653416(CHEMBL6103295)
Affinity DataKi:  0.400nMAssay Description:Antagonist activity at human cloned oxytocin receptor by cell based beta-lactamase assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653416BDBM50653416(CHEMBL6103295)
Affinity DataKi:  0.5nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V2 receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653416BDBM50653416(CHEMBL6103295)
Affinity DataKi:  0.700nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653416BDBM50653416(CHEMBL6103295)
Affinity DataIC50: 5.70nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed