BDBM50653413 CHEMBL6101825

SMILES Clc1ccc2c(c1)CC1(Cc3nnc(N4CCN(c5cccc6c5OCC6)CC4)n3-2)OCCO1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50653413   

TargetVasopressin V1a receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653413BDBM50653413(CHEMBL6101825)
Affinity DataKi:  0.130nMAssay Description:Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Mouse)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653413BDBM50653413(CHEMBL6101825)
Affinity DataKi:  0.5nMAssay Description:Inhibition of 14-3-3sigma (unknown origin) assessed as reduction in 14-3-3sigma- mediated increase in MMP1 mRNA by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V2 receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653413BDBM50653413(CHEMBL6101825)
Affinity DataKi:  0.530nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653413BDBM50653413(CHEMBL6101825)
Affinity DataIC50: 2.20nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed