BDBM50653229 CHEMBL6120714

SMILES COc1ccc(CN2[C@@H]3C[C@H]2CN(c2ccc(-c4cc(OCC5CCN(C(=O)CCCCCCN6CCC(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8)CC6)CC5)cn5ncc(C#N)c45)cn2)C3)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50653229   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653229BDBM50653229(CHEMBL6120714)
Affinity DataIC50: 1nMAssay Description:Agonist activity at human PPARgamma receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653229BDBM50653229(CHEMBL6120714)
Affinity DataIC50: 1.30nMAssay Description:Agonist activity at human PPARgamma receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653229BDBM50653229(CHEMBL6120714)
Affinity DataIC50: 49nMAssay Description:Agonist activity at mouse PPARgamma receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein cereblon(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653229BDBM50653229(CHEMBL6120714)
Affinity DataIC50: 280nMAssay Description:Displacement of radioligand from human recombinant adenosine A3 receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed