BDBM50653220 CHEMBL6144813

SMILES COC1(C(=O)N[C@@H](CCCNC(=O)CCCCCCN2CCN(c3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4)CC2)c2ccc(-n3cc(F)cn3)nc2)CCN(c2nc(C)cc(Nc3cc(C)[nH]n3)n2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50653220   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653220BDBM50653220(CHEMBL6144813)
Affinity DataIC50: 1.40nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653220BDBM50653220(CHEMBL6144813)
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human vasopressin V2 receptor by cell based beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProtein cereblon(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653220BDBM50653220(CHEMBL6144813)
Affinity DataIC50: 294nMAssay Description:Displacement of radioligand from human recombinant adenosine A3 receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653220BDBM50653220(CHEMBL6144813)
Affinity DataIC50: 594nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed