BDBM50647997 CHEMBL5287669

SMILES O=C1C2=C(CCN(Cc3ccccc3)C2)N2CCN=C2N1Cc1ccc(C(F)(F)F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50647997   

TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647997BDBM50647997(CHEMBL5287669)
Affinity DataEC50:  156nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647997BDBM50647997(CHEMBL5287669)
Affinity DataEC50:  390nMAssay Description:Activation of human recombinant his-sumo tagged ClpP expressed in Escherichia coli BL21 (DE3) using FITC-casein as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647997BDBM50647997(CHEMBL5287669)
Affinity DataEC50:  720nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647997BDBM50647997(CHEMBL5287669)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647997BDBM50647997(CHEMBL5287669)
Affinity DataEC50:  1.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647997BDBM50647997(CHEMBL5287669)
Affinity DataEC50:  3.97E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed