BDBM50647814 CHEMBL5591124

SMILES CN1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccccc4P(C)(C)=O)n3)cc2Br)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50647814   

TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647814BDBM50647814(CHEMBL5591124)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647814BDBM50647814(CHEMBL5591124)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of EGFR Del19/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647814BDBM50647814(CHEMBL5591124)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed