BDBM50646751 CHEMBL5593239

SMILES COc1ccc2ncc(F)c(CCN3CCC(C(N)Cc4ccc(C)cc4)CC3)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50646751   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Ohio State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646751BDBM50646751(CHEMBL5593239)
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
Ohio State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646751BDBM50646751(CHEMBL5593239)
Affinity DataIC50: 8.26E+4nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-IV assessed as reduction in decatenation using kinetoplast DNA as substrate incubated for 20 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Ohio State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646751BDBM50646751(CHEMBL5593239)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pBR322 DNA as substrate incubated at 37 degreeC for 30 to 45 mins followed by incubation at 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed