BDBM50643838 CHEMBL5584189

SMILES CN(C)C/C=C/C(=O)Nc1ccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2c1-c1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50643838   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643838BDBM50643838(CHEMBL5584189)
Affinity DataIC50: 2.70nMAssay Description:Agonist activity at Homo sapiens (human) 5-HT2C receptor assessed as 5-HT-induced phosphoinositide hydrolysis by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643838BDBM50643838(CHEMBL5584189)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of wild type HER2 (unknown origin) using 4 x ULightTM-labeled Ploy GT peptide substrate measured after 180 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643838BDBM50643838(CHEMBL5584189)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of wild type EGFR (unknown origin) using 4 x ULightTM-labeled JAK-1 (Try1023) peptide substrate measured after 180 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643838BDBM50643838(CHEMBL5584189)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of 1,10-phenanthrolin-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed