BDBM50641711 CHEMBL5594994

SMILES Clc1ccc2c(c1)CC1(Cc3nnc([C@H]4CC[C@H](Oc5ccccn5)CC4)n3-2)OCCO1

InChI Key InChIKey=LFXCGLFTXRJJLT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50641711   

TargetVasopressin V1a receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641711BDBM50641711(CHEMBL5594994)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]vasopressin from human V1A receptor assessed as inhibition constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641711BDBM50641711(CHEMBL5594994)
Affinity DataKi:  0.300nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641711BDBM50641711(CHEMBL5594994)
Affinity DataIC50: 0.900nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetVasopressin V1a receptor(Mouse)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641711BDBM50641711(CHEMBL5594994)
Affinity DataKi:  1.10nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetOxytocin receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641711BDBM50641711(CHEMBL5594994)
Affinity DataKi:  16nMAssay Description:Binding affinity to human Oxytocin receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVasopressin V2 receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641711BDBM50641711(CHEMBL5594994)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]AVP from human Vasopressin V2 receptor assessed as dissociation constant by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVasopressin V2 receptor(Human)
Gedeon Richter Plc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641711BDBM50641711(CHEMBL5594994)
Affinity DataKi:  40nMAssay Description:Inhibition of farnesyl transferase in NIH3T3 cell based assay in non-reducing (-DTT) conditionsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed