BDBM50636536 CHEMBL5559782

SMILES O=C([O-])c1ccc(-c2nnc(SCc3c(Cl)cccc3Cl)s2)cc1

InChI Key InChIKey=KFIUJWYVLYQUOY-UHFFFAOYSA-M

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50636536   

TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636536BDBM50636536(CHEMBL5559782)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse PIEZO1 transfected in HEK293-T-REx cells assessed as activation of intracellular Ca2+ levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636536BDBM50636536(CHEMBL5559782)
Affinity DataEC50:  150nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed