BDBM50634553 CHEMBL5412864

SMILES C[C@@H](N(C)C)C(=O)Nc1cc2CC(CNCCC3CN(C(=O)O3)c3cnc4OCC(=O)Nc4n3)Cc2c(F)c1

InChI Key InChIKey=KYOIGEZIXURVNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634553   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Roche Pharma Research & Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634553BDBM50634553(CHEMBL5412864)
Affinity DataIC50: 26nMAssay Description:Inhibition of Escherichia coli DNA gyrase incubated for 80 mins by Transcreener ADP2 FI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Roche Pharma Research & Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634553BDBM50634553(CHEMBL5412864)
Affinity DataIC50: 38nMAssay Description:Inhibition of Escherichia coli DNA gyrase incubated for 80 mins by Transcreener ADP2 FI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed