BDBM50633265 CHEMBL5406927

SMILES COc1ccc2nccc(OC[C@@H]3CC[C@H](CO3)NC(=O)c3cc(F)c(Br)c(F)c3)c2n1

InChI Key InChIKey=NHXTWWVJRWMAAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50633265   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633265BDBM50633265(CHEMBL5406927)
Affinity DataIC50: 185nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633265BDBM50633265(CHEMBL5406927)
Affinity DataIC50: 341nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 relaxation activity measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633265BDBM50633265(CHEMBL5406927)
Affinity DataIC50: 365nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling incubated for 30 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed