BDBM50631429 CHEMBL5413380

SMILES COC[C@@H](CC(C)C)NC1=N\C(=C/c2cnc3ncsc3c2)C(=O)N1

InChI Key InChIKey=LTXUUTWWWRMQRN-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50631429   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 8.75E+3nMAssay Description:Inhibition of human DYRK1A assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation counting based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CLK4 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation counting based ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DYRK1B assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation counting based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CLK1 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation counting based ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 5(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CK1 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CLK2 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK3(Homo sapiens)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CLK3 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DYRK2 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DYRK3 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 4(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DYRK4 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3(Human)
Perha Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50631429BDBM50631429(CHEMBL5413380)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GSK3 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed