BDBM50629256 CHEMBL4595425

SMILES Cn1nccc1-c1ccc(C(=O)N[C@@H]2CNCC[C@H]2c2ccc(F)c(F)c2)c(F)c1

InChI Key InChIKey=PALTUSLCLFDFQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50629256   

TargetRAC-gamma serine/threonine-protein kinase(Human)
China-Japan Union Hospital of Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetRho-associated protein kinase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 306nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 337nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
China-Japan Union Hospital of Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
China-Japan Union Hospital of Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China-Japan Union Hospital of Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
China-Japan Union Hospital of Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTestis-specific serine/threonine-protein kinase 1(Human)
China-Japan Union Hospital of Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetALK tyrosine kinase receptor(Human)
China-Japan Union Hospital of Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629256BDBM50629256(CHEMBL4595425)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed