BDBM50623918 CHEMBL5398215

SMILES CC(=O)N1CC2(CC(C2)Nc2cc3C(=O)N(C[C@H](O)CN4CCc5ccccc5C4)CC4(CC4)c3cn2)C1

InChI Key InChIKey=PEYPSWDNEDTZFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50623918   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataKd:  3.60nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 50nMAssay Description:Inhibition of PRMT5 (unknown origin) using H4(1-21)S1ac as substrate preincubated for 15 mins followed by substrate addition and measured for 60 mins...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623918BDBM50623918(CHEMBL5398215)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed