BDBM50622908 CHEMBL5410107

SMILES CCn1cc(cn1)-c1ccc2n(cnc2c1)-c1cc(OC)c(C(=O)N(C)C2CC2)c(OC)c1

InChI Key InChIKey=NJMKEYLTIHAWEP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50622908   

TargetSerine/threonine-protein kinase SIK3(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622908BDBM50622908(CHEMBL5410107)
Affinity DataIC50: 164nMAssay Description:Inhibition of human SIK3 isoform 1 (59 to 1321 residues) expressed in Sf9 insect cells using AMARA peptide as substrate incubated for 120 mins in pre...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622908BDBM50622908(CHEMBL5410107)
Affinity DataIC50: 597nMAssay Description:Inhibition of SIK2 (unknown origin) using AMARA peptide as substrate incubated for 120 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622908BDBM50622908(CHEMBL5410107)
Affinity DataIC50: 763nMAssay Description:Inhibition of SIK1 (unknown origin) using AMARA peptide as substrate incubated for 120 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622908BDBM50622908(CHEMBL5410107)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed