BDBM50611459 CHEMBL5277565

SMILES Cc1nn(C)cc1-c1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1Cl

InChI Key InChIKey=GEQMDKKVXALFFX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50611459   

TargetCyclin-dependent kinase 5 activator 1(Human)
University of South Australia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611459BDBM50611459(CHEMBL5277565)
Affinity DataKi:  2nMAssay Description:Inhibition of CDK5/p25 (unknown origin) assessed as inhibition constant incubated for 30 to 60 mins presence of dithiothreitol by Cheng-Prusoff equat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50611459BDBM50611459(CHEMBL5277565)
Affinity DataKi:  12nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) assessed as inhibition constant incubated for 30 to 60 mins presence of dithiothreitol by Cheng-Prusoff ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Human)
University of South Australia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611459BDBM50611459(CHEMBL5277565)
Affinity DataKi:  16nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) assessed as inhibition constant incubated for 30 to 60 mins presence of dithiothreitol by Cheng-Prusoff ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed