BDBM50599470 CHEMBL5179796

SMILES Oc1ccc2nc(NC(=O)Nc3ccc(NC(=O)Cc4ccccc4)cc3)sc2c1

InChI Key InChIKey=HCNOPAFXBMHAAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599470   

LigandChemical structure of BindingDB Monomer ID 50599470BDBM50599470(CHEMBL5179796)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at estrogen receptor beta (unknown origin) assessed as inhibition of estradiol-induced response after 22 hrs by cell-based lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50599470BDBM50599470(CHEMBL5179796)
Affinity DataIC50: 20nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50599470BDBM50599470(CHEMBL5179796)
Affinity DataIC50: 690nMAssay Description:Inhibition of DYRK1A in human HeLa cells transiently expressing GFP-SF3B1 fusion protein assessed as reduction in SF3B1 phosphorylation incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed