BDBM50599469 CHEMBL5179350

SMILES Oc1ccc2nc(NC(=O)Nc3ccc(NS(=O)(=O)c4cccc(F)c4)cc3)sc2c1

InChI Key InChIKey=LOKRCIGUPSXJKK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599469   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Nirma University

Curated by ChEMBL

LigandBDBM50599469(CHEMBL5179350)Copy SMILESCopy InChI

Affinity DataIC50: 45nMAssay Description:Antagonist activity at estrogen receptor beta (unknown origin) assessed as inhibition of estradiol-induced response after 22 hrs by cell-based lucife...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Copy reaction URL

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Nirma University

Curated by ChEMBL

LigandBDBM50599469(CHEMBL5179350)Copy SMILESCopy InChI

Affinity DataIC50: 45nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
Copy BDB DOIPubMed
Copy reaction URL