BDBM50597837 CHEMBL5196629

SMILES Oc1ccc(cc1O)-c1cnc2[nH]cc(-c3ccc(F)c(F)c3)c2c1

InChI Key InChIKey=SZRVXIVKDKMTQJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597837   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
West China Hospital

Curated by ChEMBL

LigandBDBM50597837(CHEMBL5196629)Copy SMILESCopy InChI

Affinity DataIC50: 57nMAssay Description:Inhibition of 6xHis-tagged rat DYRK1A (1 to 502 residues) expressed in Escherichia coli BL21(DE3) using FKHR as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/22/2023
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Nirma University

Curated by ChEMBL

LigandBDBM50597837(CHEMBL5196629)Copy SMILESCopy InChI

Affinity DataIC50: 5.66E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Copy reaction URL