BDBM50589144 CHEMBL5208686

SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(cc2)-c2ccc(=O)[nH]n2)ccc1Cl

InChI Key InChIKey=YMADNUCXSKBZJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589144   

TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50589144BDBM50589144(CHEMBL5208686)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of VEGFR2 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 1 hr in presence of ATP by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50589144BDBM50589144(CHEMBL5208686)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed