BDBM50572197 CHEMBL4879088

SMILES COc1ccc2nccc(CCN3CCC(CC3)NCc3cc(F)c(Cl)c(F)c3)c2n1

InChI Key InChIKey=GFQDXSUJWFUHQT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50572197   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572197BDBM50572197(CHEMBL4879088)
Affinity DataIC50: 14nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute of Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572197BDBM50572197(CHEMBL4879088)
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]-N-methyl-scopolamine from human muscarinic M3 receptor after 6 hrs by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572197BDBM50572197(CHEMBL4879088)
Affinity DataIC50: 172nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetTopoisomerase IV(Staphylococcus aureus)
National Institute of Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572197BDBM50572197(CHEMBL4879088)
Affinity DataIC50: 215nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed