BDBM50565474 CHEMBL4781365

SMILES C1[C@H](COC1=O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O

InChI Key InChIKey=MQEPWBMWFIVRPS-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50565474   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565474BDBM50565474(CHEMBL4781365)
Affinity DataIC50: 5.14E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using IR5 (1142 to 1153, pY1146) as substrate by malachite gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565474BDBM50565474(CHEMBL4781365)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565474BDBM50565474(CHEMBL4781365)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant SHP2 (unknown origin) using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565474BDBM50565474(CHEMBL4781365)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human TCPTP using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed