BDBM50546170 CHEMBL4759108

SMILES Fc1ccc(-c2nnc(o2)N2CCN(CC2)c2ccccn2)c(F)c1

InChI Key InChIKey=JDYATWHUSHCNRV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50546170   

TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546170BDBM50546170(CHEMBL4759108)
Affinity DataKi:  30nMAssay Description:Mixed type inhibition of human erythrocytes AChE using varying levels of acetylthiocholine iodide substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546170BDBM50546170(CHEMBL4759108)
Affinity DataIC50: 54nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546170BDBM50546170(CHEMBL4759108)
Affinity DataIC50: 98nMAssay Description:Inhibition of human BACE-1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate preincubated with substrate followed by enzyme addition by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546170BDBM50546170(CHEMBL4759108)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetBeta-secretase 1(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546170BDBM50546170(CHEMBL4759108)
Affinity DataIC50: 210nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50546170BDBM50546170(CHEMBL4759108)
Affinity DataIC50: 787nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed