BDBM50527899 CHEMBL4475041

SMILES C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OP(=O)(O)O)O)OP(=O)(O)O)OP(=O)(O)O)O

InChI Key InChIKey=IXJMLEYTDGNHLU-UHFFFAOYSA-N

Data  2 Kd  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50527899   

TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527899BDBM50527899(CHEMBL4475041)
Affinity DataKd:  11nMAssay Description:Displacement of [3H]-IP3 from IP3R1 in Wistar rat cerebellar membrane measured after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527899BDBM50527899(CHEMBL4475041)
Affinity DataKd:  11nMAssay Description:Displacement of [3H]-IP3 from IP3R1 in Wistar rat cerebellar membrane measured after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527899BDBM50527899(CHEMBL4475041)
Affinity DataEC50:  80nMAssay Description:Agonist activity at rat IP3R1 expressed in HEK cells assessed as increase in calcium release in cytosol by measuring fluorescence signal by Mag-Fluo4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rat)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527899BDBM50527899(CHEMBL4475041)
Affinity DataEC50:  81nMAssay Description:Agonist activity at rat IP3R1 expressed in HEK cells assessed as increase in calcium release in cytosol by measuring fluorescence signal by Mag-Fluo4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed