BDBM50476150 CHEMBL221659

SMILES C[C@@H]1OC(=O)NN=C1c1ccc(-n2cc(C(F)(F)F)cn2)c(C(F)(F)F)c1

InChI Key InChIKey=AYUXVBYIMHDOMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476150   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Broad Institute of MIT and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476150BDBM50476150(CHEMBL6074447)
Affinity DataIC50: 607nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using NADPH assessed as conversion of cortisone to cortisol by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed