BDBM50438305 CHEMBL2408585

SMILES Clc1cccc(Nc2ncc3C(=O)CCCc3n2)c1

InChI Key InChIKey=PSIUKUAVWWOLJH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50438305   

TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438305BDBM50438305(CHEMBL2408585)
Affinity DataIC50: 120nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Padova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438305BDBM50438305(CHEMBL2408585)
Affinity DataKi:  340nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells assessed as inhibition constant using kynuramine as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Padova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438305BDBM50438305(CHEMBL2408585)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells assessed as inhibition constant using kynuramine as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed