BDBM50412977 CHEMBL517391

SMILES Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2C2=CCC3(CC2)CC3)nc(N2CCC(F)(F)CC2)n1

InChI Key InChIKey=AVJHHZKCFDWAHM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412977   

TargetKinesin-like protein KIF18A(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412977BDBM50412977(CHEMBL6074553)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetKinesin-like protein KIF11(Human)
Changchun Genescience Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412977BDBM50412977(CHEMBL6074553)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed